Outcomes Related to Mucosal Healing in Patients With Crohn's Disease
نویسندگان
چکیده
منابع مشابه
Mucosal healing in patients with celiac disease and outcomes of pregnancy: a nationwide population-based study.
BACKGROUND & AIMS Studies have associated undiagnosed celiac disease with adverse outcomes of pregnancy. We investigated the association between persistent villous atrophy and outcomes of pregnancy in women with celiac disease. METHODS We collected data on 337 women with celiac disease who gave birth (to 460 infants) within 5 years of a follow-up biopsy, from 28 pathology departments in Swede...
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Purpose: MR enterography (MRE) is one of the mainstays in the evaluation of Crohns disease (CD). A wide variety of studies have attempted to improve the sensitivity and specificity of MRE, all focusing on the evaluation of static images [1]. MRE however allows not only the static display of morphology, but can be combined with ultrafast scanning techniques (cineMRE) for analysis of bowel motili...
متن کاملAdalimumab for endoscopic and histopathological mucosal healing in paediatric patients with moderate to severe Crohn’s disease
INTRODUCTION Deep remission, defined as clinical remission with mucosal healing (MH), with anti-tumor necrosis factor (TNF)-α agents is a new target for therapy in Crohn's disease (CD). Provided that the efficacy of infliximab (IFX) for induction of MH in CD has been demonstrated, there are much less data for adalimumab (ADA), and none concerning MH on histopathological examination. AIM To as...
متن کاملMucosal healing and mortality in coeliac disease.
BACKGROUND Coeliac disease (CD), characterised by the presence of villous atrophy (VA) in the small intestine, is associated with increased mortality, but it is unknown if mortality is influenced by mucosal recovery. AIMS To determine whether persistent VA is associated with mortality in CD. METHODS Through biopsy reports from all pathology departments (n = 28) in Sweden, we identified 7648...
متن کاملTargeting mucosal healing in Crohn's disease.
The goal of medical treatment for Crohn's disease includes improving patients' quality of life while reducing the need for hospitalization and surgery. The current medical armamentarium includes 5-aminosalicylates, corticosteroids, immunomodulators, and biologic agents. In the past, response to treatment was measured by clinical improvement in symptoms; however, with the advent of disease-modif...
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ژورنال
عنوان ژورنال: Clinical Gastroenterology and Hepatology
سال: 2020
ISSN: 1542-3565
DOI: 10.1016/j.cgh.2020.10.049